Jays DH Frank Thomas hit a pair of home runs and outfielder Vernon Wells also went deep, but a 2 run 7th inning help lead the A's to victory.
Jays pitcher Dustin McGowan saw his record fall to 8-8 on the season.
Toronto now sits 9 games back of Seattle in the American League Wildcard.
Toronto and Oakland will wrap up their 3 game series this morning as the Jays look to avoid the sweep.
Toronto sends 7-6 A.J. Burnett to the mound.
You can listen to the game on Your Voice of the Blue Jays AM 1190 starting at 10:30.
For more information on your Blue Jays go to www.torontobluejays.com